Frequently Asked Questions
What is a fecal microbiota transplant (FMT)?
A fecal microbiota transplant (FMT), also called fecal transplant, is the transfer of stool from a healthy donor to the GI tract of a sick recipient. The stool from the donor contains a diverse, well-functioning community of bacteria that take up residence in the recipient’s gut. FMT is the best known approach for restoring a balanced gut microbiome and has proven to be an effective treatment in both humans and companion animals.
FMT has been used for hundreds of years in veterinary medicine and for over a thousand years in human medicine. Though modern regulatory entities like the Food and Drug Administration (FDA) are still determining how to classify it, FMT continues to demonstrate beneficial results for a growing list of human health conditions. For example, FMT is routinely used to treat Clostridioides difficile (C. diff) infections. And it provides a promising solution for the low gut bacterial diversity associated with Crohn’s disease (a form of IBD).
What are Gut Restore/FMT capsules (poop pills)?
An FMT can be delivered via colonoscopy or enema, but for cats and dogs, those procedures generally require sedation. Our Gut Restore Supplement is an oral FMT capsule that gives your dog the benefits of FMT without the need for surgery or sedation. Containing a proprietary mixture of carefully screened, cryoprotected, freeze-dried donor stool, the Gut Restore capsules (aka “poop pills”) offer a noninvasive, affordable, at-home alternative for pets suffering from digestive, skin, or immune system issues.
How can the Gut Restore Supplement improve my dog’s health?
By seeding your dog’s microbiome with all the right bacteria in the right proportions, the capsules can help reestablish balance and resolve symptoms. While it varies depending on underlying health conditions, positive results—such as better formed stool, improved appetite, and less itching.
When dogs with digestive symptoms, skin issues, or immune system problems turn out to be missing certain important gut bacteria, we need to add those missing members to the microbiome and help the new populations grow and thrive.
The Gut Restore Supplement provides a whole community of healthy dog-specific microbes. The capsule’s enteric coating prevents it from dissolving until it reaches the intestines, where the contents “seed” your dog’s gut with a diverse array of healthy bacteria, restoring any missing groups.
Where do you get the material for Gut Restore Supplements?
Our Gut Restore Supplements for dogs are derived from stool donated by healthy pet dogs that live in homes and have been carefully screened for health, age, fecal consistency, behavior, and microbiome composition (based on DNA sequencing).
Donor stool samples are submitted for parasites and pathogen screening to the Idexx Reference Laboratories, the leading veterinary diagnostics company, which has stringent quality control guidelines and well-validated standard operating procedures.
All dog donor material is regularly screened for parasites and pathogens:
- Dogs are screened for the following pathogens via PCR: Clostridium perfringens CPnetEF toxin gene, Clostridium perfringens Enterotoxin Gene, Campylobacter coli, Campylobacter jejuni, canine distemper virus, canine enteric coronavirus, canine parvovirus 2, canine circovirus, Clostridium difficile toxin A, Clostridium difficile toxin B, Cryptosporidium spp., Giardia spp., Salmonella spp.
- Dogs are screened for the following parasites via ELISA: Hookworms, Roundworms, and Whipworms
- Dogs are screened for ova and parasites using fecal floatation.
Is the supplement right for my dog?
An extremely wide range of dogs have benefited from the Gut Restore Supplement, ranging in age from 2 months to 17 years. The vast majority of dogs see improvement in their digestive issues, food allergies and intolerances, and/or skin issues.
While this supplement is natural and intended to gently repopulate the microbiome, it does contain high numbers of healthy bacteria that can be overwhelming to medically unstable dogs. If your dog is severely underweight or requires frequent hospitalization, we recommend checking with your veterinarian to see if the supplement is right for your dog.
Will this supplement help my dog?
About 80% of dogs that take the Gut Restore Supplement see a significant improvement in their symptoms. However, every dog is different, and the Gut Restore Supplement is not effective for every dog. And in some cases, it can take up to two months to start seeing an improvement.
Can I open or crush the capsules to mix the powder in with food?
We strongly recommend giving the capsules whole, because the outer capsule has an acid-resistant coating that protects the bacteria during their journey through the stomach.
Can I continue my dog's other medications or supplements?
Most medications and supplements can be continued, with two main exceptions:
(1) Bacterial probiotics (e.g., Lactobacillus, Enterococcus) should be discontinued when possible, as these bacteria compete with the dog-specific bacteria. As an alternative, the yeast probiotic, Saccharomyces boulardii, can be used because it supports dog-specific bacteria in the supplement.
(2) Antibiotics make the Gut Restore Supplement less effective. If your dog is on long-term antibiotics, talk to your veterinarian to see if you can taper down the dosing. However, some dogs improve even while taking antibiotics, so discontinuing them is not essential.
Still have questions? Please contact us. We are happy to work with you and/or your veterinarian.
I have a 3 year old Golden Retriever who has been on and off metronaidazole since he was 8 weeks old. We have tried all sorts of over the counter stuff and finally did some extensive (and expensive!) blood work and sent off poop samples. Nothing definitive came back and his vet and I talked about a fecal transplant being my last resort. In doing research I found this product. He is in his 2nd month of taking it and has had only one episode of diarreah. I will keep him on it and hope for the best but so far I'd say it's working.
My 15 year old little dog became very ill and 3 vets and 1 vet specialist could not determine what happened. Ultrasound revealed extreme inflammation in his gastrointestinal system. We started him on Doggie Biome and within 5-6 days we were making progress with his severe watery diarrhea. He also needed a low dose steroid to address the inflammation. He is back to his bouncy self. We were concerned that we wouldn’t be able to get the Doggie Biome capsule down his throat but putting it in a little cold butter does the trick. Easy! I am grateful this product exists and won’t hesitate to use it again.
My young doodle had chronic diarrhea and was loosing weight. I am a veterinarian and had done all of the standard treatments and testing with no relief of symptoms. Within a week of starting the FMT capsules he began having formed stools and stopped the weight loss. I kept him on it for 2 months ( mostly normal stools) and weaned him off 2 months ago and he is still doing great and has gained weight. I credit this product entirely for his turn around!
My dog was undergoing chemo for lymphoma and was having severe diarrhea as a side effect. The vet prescribed multiple different meds to try and help—even let me give her Imodium, which she said she didn’t like dogs to take—but nothing stopped the diarrhea. Finally the oncologist suggested Animal Biome. It is expensive, but it worked. When my dog’s cancer recurred, I started her back on Animal Biome prior to starting chemo and she didn’t have any diarrhea. Sad to say the chemo didn’t work this time around, but I’m glad that while trying to get her to remission a second time, at least she didn’t have to suffer with diarrhea.
My 12 year old Aussie had Giardia, then a vestibular episode followed by a bout with Clostridium. During that time we also had to put our 17 year old Aussie down and this all happened around the 4th of July and he is terrified of fireworks. Tough time. I asked my vet about fecal transplant and she just said to use various drugs she gave me. Everything medically was cleared up but he still had terrible diarrhea for weeks. He could barely walk, would fall over. It was terrifying. Had a harness on him 24/7 to help him up and to walk. Finally I listened to my dog's chiropractor, who is also a vet, and started this product 2x/day for 30 days. At the end of 30 days his poop was better but not great. Took another week or so but he is back to his usually goofy self. He can get up and walk by himself, on walks he barks at other dogs which is still annoying but great because he's back to himself again. He can talk a long walk, mile plus, with the other dogs. LOVE THIS PRODUCT!